OK, a disclaimer: I like Python, and I've used KDE/Qt before (with success, in C++), but I dislike GUI-programming with a vengance! With that out of my system, I must admit that this book made GUI programming a pleasure, in combination with Python (which I've used with TK and wxWindows before).

Anyway, beware that even though the book is pretty big, it doesn't in any way contain the detailed descriptions of the interfaces, as you must read these from the "official" Qt -documentation, which is geared to C++. It is a very good tutorial and overview, not the last word on the documentation of PyQt as the sub-title may lead you to believe.

Anyway, ity achieves it aims, and I give it my strong recommendation.